Yihai Cao Selected Research

Angiogenesis Inhibitors

1/2019	Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
3/2011	Antiangiogenic agents significantly improve survival in tumor-bearing mice by increasing tolerance to chemotherapy-induced toxicity.
10/2009	Improvement of antiangiogenic cancer therapy by understanding the mechanisms of angiogenic factor interplay and drug resistance.
7/2008	R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways.
1/2008	Molecular mechanisms and therapeutic development of angiogenesis inhibitors.
9/2007	Angiogenesis modulates adipogenesis and obesity.
6/2004	Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice.
4/2004	Antiangiogenic cancer therapy.
2/2004	Angiostatin.
1/2003	The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis.

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Yihai Cao Research Topics

Disease

95	Neoplasms (Cancer) 11/2022 - 02/2002
32	Neoplasm Metastasis (Metastasis) 11/2022 - 02/2002
14	Hypoxia (Hypoxemia) 10/2021 - 06/2006
9	Breast Neoplasms (Breast Cancer) 11/2021 - 11/2008
9	Obesity 01/2018 - 02/2004
9	Lymphatic Metastasis 09/2014 - 06/2002
8	Vascular Remodeling 01/2020 - 02/2005
7	Pathologic Neovascularization 10/2017 - 06/2004
6	Inflammation (Inflammations) 01/2022 - 07/2002
6	Colorectal Neoplasms (Colorectal Cancer) 11/2021 - 09/2008
6	Fibrosarcoma 01/2020 - 02/2002
5	Retinal Neovascularization 10/2017 - 03/2008
4	Insulin Resistance 10/2014 - 06/2004
3	Melanoma (Melanoma, Malignant) 11/2021 - 06/2015
3	Ischemia 01/2020 - 05/2003
3	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 04/2006
3	Fibrosis (Cirrhosis) 11/2017 - 08/2011
3	Anemia 10/2014 - 12/2011
2	Infections 12/2022 - 10/2021
2	Atherosclerosis 04/2022 - 01/2019
2	Vomiting 11/2021 - 01/2019
2	Nausea 11/2021 - 01/2019
2	COVID-19 10/2021 - 01/2021
2	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2019
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 06/2015
2	Adenocarcinoma of Lung 01/2021 - 08/2012
2	Leukemia 07/2020 - 01/2019
2	Atherosclerotic Plaque (Atheroma) 01/2019 - 07/2013
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 10/2018 - 10/2014
2	Retinal Degeneration 10/2018 - 10/2014
2	Cataract (Cataracts) 11/2017 - 01/2017
2	Body Weight (Weight, Body) 01/2014 - 04/2006
2	Ocular Paraneoplastic Syndromes 05/2010 - 01/2010
2	Stroke (Strokes) 04/2010 - 03/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2010 - 03/2008
1	Wounds and Injuries (Trauma) 12/2022

Drug/Important Bio-Agent (IBA)

41	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2022 - 02/2002
20	Pharmaceutical PreparationsIBA 12/2022 - 01/2007
16	Proteins (Proteins, Gene)FDA Link 12/2022 - 04/2002
12	Angiogenesis InhibitorsIBA 01/2019 - 07/2002
11	Becaplermin (PDGF-BB)FDA Link 01/2018 - 05/2003
11	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2015 - 10/2004
10	Oxygen (Dioxygen)IBA 01/2022 - 06/2006
9	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2021 - 06/2002
7	Bevacizumab (Avastin)FDA Link 01/2021 - 01/2008
6	Biological ProductsIBA 12/2022 - 12/2009
6	CytokinesIBA 01/2021 - 02/2005
6	Retinaldehyde (Retinal)IBA 01/2020 - 07/2008
6	Sunitinib (Sutent)FDA Link 01/2016 - 07/2008
4	Interleukin-33IBA 01/2022 - 01/2016
4	Vascular Endothelial Growth Factor BIBA 10/2018 - 03/2008
4	Vascular Endothelial Growth Factor CIBA 09/2012 - 06/2002
4	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2010 - 10/2005
4	LigandsIBA 01/2010 - 06/2002
3	Tyrosine Kinase InhibitorsIBA 01/2021 - 12/2018
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2013
3	IntegrinsIBA 01/2020 - 03/2014
3	Estrogen ReceptorsIBA 10/2019 - 08/2015
3	LipidsIBA 01/2019 - 07/2013
3	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 12/2018 - 01/2013
3	Blocking AntibodiesIBA 12/2018 - 01/2013
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 12/2018 - 07/2010
3	Erythropoietin FDA Link 11/2017 - 12/2011
3	MorpholinosIBA 11/2015 - 11/2009
3	platelet-derived growth factor C (PDGF-C)IBA 10/2014 - 04/2010
3	FilaminsIBA 02/2014 - 03/2007
3	Angiogenesis Modulating AgentsIBA 01/2014 - 01/2009
3	Small Interfering RNA (siRNA)IBA 01/2013 - 07/2010
3	Platelet-Derived Growth FactorIBA 01/2013 - 02/2005
2	HydrogelsIBA 12/2022 - 01/2018
2	Messenger RNA (mRNA)IBA 01/2022 - 12/2011
2	RNA (Ribonucleic Acid)IBA 01/2022 - 09/2008
2	Hormones (Hormone)IBA 11/2021 - 12/2009
2	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 11/2021 - 01/2019
2	AntigensIBA 11/2021 - 05/2010
2	Polo-Like Kinase 1IBA 01/2021 - 01/2021
2	Phosphorus (Red Phosphorus)IBA 11/2020 - 01/2018
2	NucleotidesIBA 01/2020 - 01/2011
2	Choline (Choline Chloride)IBA 10/2019 - 10/2016
2	LDL Receptors (LDL Receptor)IBA 01/2019 - 07/2013
2	Apolipoproteins E (ApoE)IBA 01/2019 - 07/2013
2	ApolipoproteinsIBA 01/2019 - 07/2013
2	Jagged-1 ProteinIBA 11/2017 - 01/2017
2	Tamoxifen FDA LinkGeneric 10/2016 - 08/2015
2	Neutralizing AntibodiesIBA 04/2016 - 07/2010
2	Microfilament Proteins (Actin Binding Proteins)IBA 02/2014 - 03/2007
2	Matrix Metalloproteinase 14 (MT1-MMP)IBA 08/2012 - 06/2012
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 08/2011 - 05/2006
2	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 11/2009 - 10/2009
2	CollagenIBA 09/2008 - 01/2003
2	EndostatinsIBA 01/2008 - 04/2002
2	Laminin (Merosin)IBA 06/2004 - 02/2002
2	AngiostatinsIBA 02/2004 - 11/2002
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2022

Therapy/Procedure

48	Therapeutics 04/2022 - 06/2002
10	Drug Therapy (Chemotherapy) 11/2021 - 01/2008
2	Immunotherapy 01/2021 - 01/2020
2	Precision Medicine 01/2021 - 01/2020
2	Radiotherapy 01/2021 - 01/2015
2	Photothermal Therapy 12/2020 - 01/2020